Cette unité d'enseignement permet aux étudiants d'être initiés sur le rôle du physiothérapeute dans la rééducation du cancer du sein, de faire le point sur les différents traitements médicaux ainsi que leurs complications, et d'obtenir une introduction aux modalités de rééducation ainsi que la rééducation des patients atteint de lymphome, d’avoir un aperçu général sur les modalités du traitement médical, surtout la greffe de la moelle osseuse et un rappel du système immunitaire.

Temps présentiel : 20 heures

Charge de travail étudiant : 30 heures

Méthode(s) d'évaluation : Examen final, Examen partiel, Travaux pratiques contrôlés

Référence :
Cancer du sein • Amal, E., Meriem, K., Mustapha, B., Mohamed, A., & Mustapha, E. M. Cancer du sein: Données Actuelles 2013. • BOUKLI-HACENE, A., ABDELALI, W., DJAAFARI, A., YAHIAOUI, M. E. A., & SHETAYA, M. pris en charge au niveau du service de gynéco-obstétrique Etude Descriptive Rétrospective Des cas de cancer du sein (Doctoral dissertation, 2014). • Bihani, T., Patel, H. K., Arlt, H., Tao, N., Jiang, H., Brown, J. L., ... & Garner, F. (2017). Elacestrant (RAD1901), a selective estrogen receptor degrader (SERD), has antitumor activity in multiple ER+ breast cancer patient-derived xenograft models. Clinical Cancer Research, 23(16), 4793-4804. • Ferrandez, J. C., & Serin, D. (2006). Rééducation et cancer du sein. Elsevier Masson. • Földi, M., Földi, E., Strößenreuther, R., & Kubik, S. (Eds.). (2012). Földi's textbook of lymphology: for physicians and lymphedema therapists. Elsevier Health Sciences. • Lakkis, N. A., Adib, S. M., Osman, M. H., Musharafieh, U. M., & Hamadeh, G. N. (2010). Breast cancer in Lebanon: Incidence and comparison to regional and Western countries. Cancer Epidemiology, 34(3), 221–225. • Macadam, S. A., & Lennox, P. A. (2012). Acellular dermal matrices: use in reconstructive and aesthetic breast surgery. Canadian Journal of Plastic Surgery, 20(2), 75-89. • Marchiò, C., Annaratone, L., Marques, A., Casorzo, L., Berrino, E., & Sapino, A. (2021, July). Evolving concepts in HER2 evaluation in breast cancer: Heterogeneity, HER2-low carcinomas and beyond. In Seminars in cancer biology (Vol. 72, pp. 123-135). Academic Press. • Salem, C., Atallah, D., Safi, J., Chahine, G., Haddad, A., El Kassis, N., ... & Ghossain, M. (2017). Breast density and breast cancer incidence in the Lebanese population: Results from a retrospective multicenter study. BioMed Research International, 2017. • Shamseddine, A., Saleh, A., Charafeddine, M., Seoud, M., Mukherji, D., Temraz, S., & Sibai, A. M. (2014). Cancer trends in Lebanon: a review of incidence rates for the period of 2003–2008 and projections until 2018. Population health metrics, 12(1), 4. • Leduc, O., Fumiere, E., Banse, S., Vandervorst, C., Clément, A., Parijs, T., ... & Leduc, A. (2014). Identification and description of the axillary web syndrome (AWS) by clinical signs, MRI and US imaging. Lymphology, 47(4), 164-176. • Josenhans, E. (2007). Physiotherapeutic treatment for axillary cord formation following breast cancer surgery. Pt_Zeitschrift für Physiotherapeuten, 59(9), 868-878. • Schmitz, K. H., Prosnitz, R. G., Schwartz, A. L., & Carver, J. R. (2012). Prospective surveillance and management of cardiac toxicity and health in breast cancer survivors. Cancer, 118(S8), 2270-2276. • Schmitz, K. H., Courneya, K. S., Matthews, C., Demark-Wahnefried, W., Galvão, D. A., Pinto, B. M., ... & Schneider, C. M. (2010). American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Medicine & Science in Sports & Exercise, 42(7), 1409-1426. • Kwan, M. L., Darbinian, J., Schmitz, K. H., Citron, R., Partee, P., Kutner, S. E., & Kushi, L. H. (2010). Risk factors for lymphedema in a prospective breast cancer survivorship study: the Pathways Study. Archives of surgery, 145(11), 1055-1063. • Schmitz, K. H., Ahmed, R. L., Troxel, A., Cheville, A., Smith, R., Lewis-Grant, L., ... & Greene, Q. P. (2009). Weight lifting in women with breast-cancer–related lymphedema. New England Journal of Medicine, 361(7), 664-673. • Lauridsen, M. C., Christiansen, P., & Hessov, I. B. (2005). The effect of physiotherapy on shoulder function in patients surgically treated for breast cancer: a randomized study. Acta oncologica, 44(5), 449-457. • Wang, Z., Wu, L. C., & Chen, J. Q. (2011). Sentinel lymph node biopsy compared with axillary lymph node dissection in early breast cancer: a meta-analysis. Breast cancer research and treatment, 129(3), 675. • Tierney, S., Aslam, M., Rennie, K., & Grace, P. (1996). Infrared optoelectronic volumetry, the ideal way to measure limb volume. European Journal of Vascular and Endovascular Surgery, 12(4), 412-417. • Prothèses mammaires et cancers. Retrieved from https://centre-maladies-sein-saint-louis.org/documents_pdf/Protheses_mammaires_cancers.pdf • The stages of breast cancer. Retrieved from https://www.mskcc.org/cancer-care/types/breast/diagnosis/stages-breast • Complementary oncology. Retrieved from https://complementaryoncology.com/reports/breast-cancer/why-is-the-progesteroneoestrogen-ratio-so-important/ • Demystifying Breast Cancer and its Treatment. Retrieved from https://onco.com/blog/demystifying-breast-cancer-and-its-treatment/ • CHUV. Retrieved from https://www.chuv.ch/fr/rad/rad-home/professionnels-de-la-sante/nos-interventions/senologie/macrobiopsie-mammaire/ • Global cancer institute. Retrieved from https://globalcancerinstitute.org/global/breast-cancer-awareness-month-2018/ • Société Canadienne du cancer. Retrieved from https://www.cancer.ca/fr-ca/cancer-information/cancer-type/breast/breast-cancer/the-breasts/?region=qc • OMS. Retrieved from https://www.who.int/cancer/fr/ • Institut National du Cancer. Retrieved from https://www.e-cancer.fr/Patients-et-proches/Les-cancers/Cancer-du-sein/Anatomie-du-sein • Institut National du Cancer. Retrieved from https://www.e-cancer.fr/Comprendre-prevenir-depister/Qu-est-ce-qu-un-cancer/Mecanisme-de-cancerisation • World Cancer Research Fund International. (2018). Breast cancer statistics. Retrieved from https://www.wcrf.org/dietandcancer/cancer-trends/worldwide-cancer-data • Breast cancer organization. Retrieved from https://www.breastcancer.org • SAVI Brachytherapy for Early-Stage Breast Cancer. Retrieved from https://www.verywellhealth.com/savi-breast-brachytherapy-device-430391 Lymphomes: • Baumann, F. T., Kraut, L., Schüle, K., Bloch, W., & Fauser, A. A. (2010). A controlled randomized study examining the effects of exercise therapy on patients undergoing haematopoietic stem cell transplantation. Bone Marrow Transplantation, 45(2), 355–362. https://doi.org/10.1038/bmt.2009.163 • Baumann, Freerk T., Zopf, E. M., Nykamp, E., Kraut, L., Schüle, K., Elter, T., Fauser, A. A., & Bloch, W. (2011). Physical activity for patients undergoing an allogeneic hematopoietic stem cell transplantation: Benefits of a moderate exercise intervention. European Journal of Haematology, 87(2), 148–156. https://doi.org/10.1111/j.1600-0609.2011.01640.x • Coleman, E. A., Coon, S., Hall-Barrow, J., Richards, K., Gaylor, D., & Stewart, B. (2003). Feasibility of Exercise During Treatment for Multiple Myeloma. Cancer Nursing, 26(5), 410–419. • DeFor, T. E., Burns, L. J., Gold, E.-M. A., & Weisdorf, D. J. (2007). A Randomized Trial of the Effect of a Walking Regimen on the Functional Status of 100 Adult Allogeneic Donor Hematopoietic Cell Transplant Patients. Biology of Blood and Marrow Transplantation, 13(8), 948–955. https://doi.org/10.1016/j.bbmt.2007.04.008 • Hodgkin’s lymphoma (Hodgkin’s disease)—Symptoms and causes. (n.d.). Mayo Clinic. Retrieved 17 March 2021, from https://www.mayoclinic.org/diseases-conditions/hodgkins-lymphoma/symptoms-causes/syc-20352646 • Information, N. C. for B., Pike, U. S. N. L. of M. 8600 R., MD, B., & Usa, 20894. (2020). What are the organs of the immune system? In InformedHealth.org [Internet]. Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/NBK279395/ • Jarden, M., Baadsgaard, M. T., Hovgaard, D. J., Boesen, E., & Adamsen, L. (2009). A randomized trial on the effect of a multimodal intervention on physical capacity, functional performance and quality of life in adult patients undergoing allogeneic SCT. Bone Marrow Transplantation, 43(9), 725–737. https://doi.org/10.1038/bmt.2009.27 • Jarden, M., Hovgaard, D., Boesen, E., Quist, M., & Adamsen, L. (2007). Pilot study of a multimodal intervention: Mixed-type exercise and psychoeducation in patients undergoing allogeneic stem cell transplantation. Bone Marrow Transplantation, 40(8), 793–800. https://doi.org/10.1038/sj.bmt.1705807 • Les Fonctions du Foie. (2014, August 14). Centre Hépato-Biliaire Paul Brousse. https://www.centre-hepato-biliaire.org/maladies-foie/fonctions-h%C3%A9patiques.html • Leukemia & Lymphoma Society. (2019). Blood_and_Marrow_Guide_2019.pdf. https://www.lls.org/sites/default/files/National/USA/Pdf/Publications/PS95_Blood_and_Marrow_Guide_2019.pdf • Mello, M., Tanaka, C., & Dulley, F. L. (2003). Effects of an exercise program on muscle performance in patients undergoing allogeneic bone marrow transplantation. Bone Marrow Transplantation, 32(7), 723–728. https://doi.org/10.1038/sj.bmt.1704227 • non hodgkins lymphoma—UpToDate. (n.d.). Retrieved 17 March 2021, from https://www.uptodate.com/contents/search?search=non%20hodgkins%20lymphoma&sp=0&searchType=PLAIN_TEXT&source=USER_INPUT&searchControl=TOP_PULLDOWN&searchOffset=1&autoComplete=false&language=&max=0&index=&autoCompleteTerm= • Wiskemann, J., Dreger, P., Schwerdtfeger, R., Bondong, A., Huber, G., Kleindienst, N., Ulrich, C. M., & Bohus, M. (2011). Effects of a partly self-administered exercise program before, during, and after allogeneic stem cell transplantation. Blood, 117(9), 2604–2613. https://doi.org/10.1182/blood-2010-09-306308 • Baris, D., & Zahm, S. H. (2000). Epidemiology of lymphomas. Current Opinion in Oncology, 12(5), 383–394. https://doi.org/10.1097/00001622-200009000-00002 • Département Cancer et Environnement. (2016). Facteurs de risques du lymphome | Cancer et environnement. https://www.cancer-environnement.fr/299-Lymphome.ce.aspx • Grulich, A. E., Vajdic, C. M., & Cozen, W. (2007). Altered Immunity as a Risk Factor for Non-Hodgkin Lymphoma. Cancer Epidemiology and Prevention Biomarkers, 16(3), 405–408. https://doi.org/10.1158/1055-9965.EPI-06-1070 • Hohenadel, K., Harris, S. A., McLaughlin, J. R., Spinelli, J. J., Pahwa, P., Dosman, J. A., Demers, P. A., & Blair, A. (2011). Exposure to Multiple Pesticides and Risk of Non-Hodgkin Lymphoma in Men from Six Canadian Provinces. International Journal of Environmental Research and Public Health, 8(6), 2320–2330. https://doi.org/10.3390/ijerph8062320 • Lymphoma Research Foundation. (2017). LRF1607-NHL-Booklet-D5V1-for-web-V2_3.9.2018.pdf. https://lymphoma.org/wp-content/uploads/2018/03/LRF1607-NHL-Booklet-D5V1-for-web-V2_3.9.2018.pdf • Organisation mondiale de la santé. (2011). Global status report on noncommunicable diseases 2010. World Health Organization. • Organisation mondiale de la Santé. (2014). Lbn_fr.profils des pays pour le cancer. https://www.who.int/cancer/country-profiles/lbn_fr.pdf?ua=1 • Roman, E., & Smith, A. G. (2011). Epidemiology of lymphomas. Histopathology, 58(1), 4–14. https://doi.org/10.1111/j.1365-2559.2010.03696.x • Shamseddine, A., Saleh, A., Charafeddine, M., Seoud, M., Mukherji, D., Temraz, S., & Sibai, A. M. (2014). Cancer trends in Lebanon: A review of incidence rates for the period of 2003-2008 and projections until 2018. Population Health Metrics, 12(1), 4. https://doi.org/10.1186/1478-7954-12-4 • Skibola, C. F. (2007). Obesity, Diet and Risk of Non-Hodgkin Lymphoma. Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 16(3), 392. https://doi.org/10.1158/1055-9965.EPI-06-1081 • World Health Organization. (2017). Guide to early cancer diagnosis. http://apps.who.int/iris/bitstream/10665/254500/1/9789241511940-eng.pdf